One
of the primary goals of the course is to introduce some of the exciting
and
integrative new discoveries in the field
of developmental biology. The aim of this paper
assignment is to provide you with the
opportunity to engage in a more in-depth analysis
of a selected topic that is of particular
interest to you. For a topic you may choose one
of the following:
(For those interested in medical applications):
1.
Development of a specific cell type (eg motor neurons, hair cells),
tissue type
(eg muscle), or organ (eg heart, teeth). The focus should be
on normal and
abnormal development of the specific cell type or organ.
2.
The role of a specific gene in normal development as well as in abnormal
development.
(For those interested in environmental developmental biology):
3.
The role of an environmental contaminant or teratogen in normal and abnormal
development.
(For those interested in evolutionary topics):
4.
The development of a specific cell type or organ analyzed phylogenetically
with
the emphasis
on delineating evolutionary comparisons.
5. The evolution of a gene or gene family.
The paper should take the form of
a review paper and should be approximately
8-10 pages in length (double-spaced).
You should consult a minimum of ten papers
from the current literature in order to
write your review paper. It should adhere to the
following guidelines:
Introduction (1-2
pgs): in which you introduce your topic and state the general
significance
of the topic.
Review of the
Literature (4-5 pgs): in which you present an organized review/analysis
of
the current state
of knowledge in the field.
Future Directions
(3-4 pgs): in which you discuss what experiments and directions
should be pursued
next.
Please note: you may have as much or as
little overlap between this assignment and
the bioinformatics assignment.